Anti-SMAD3 Antibody [PCRP-SMAD3-1A2] - BSA and Azide free
Description
Mouse monoclonal [PCRP-SMAD3-1A2] antibody to SMAD3.
Specificity
Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGF-mediated phosphorylation of other Smad family members.
Flow cytometric analysis of PFA fixed HeLa cells using Anti-SMAD3 Antibody [PCRP-SMAD3-1A2] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Unstained cells (red).
Immunofluorescent analysis of PFA fixed HeLa cells stained with Anti-SMAD3 Antibody [PCRP-SMAD3-1A2] followed by Goat Anti-Mouse IgG (CF® 488) (Green). Counterstain is Phalloidin-CF® 640A (Red).
Anti-SMAD3 Antibody [PCRP-SMAD3-1A2] - BSA and Azide free (A252450)
Analysis of protein array containing more than 19,000 full-length human proteins using Anti-SMAD3 Antibody [PCRP-SMAD3-1A2]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
SDS-PAGE analysis of Anti-SMAD3 Antibody [PCRP-SMAD3-1A2] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
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