This antibody recognises PTPN11 also known as tyrosine-protein phosphatase non-receptor type 11, PTP2C or SHPTP2. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPN11 contains two Src homology-2 domains which bind phospho-tyrosine domains. PTPs regulate numerous cellular functions including cell proliferation and oncogenic transformation.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:1,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human PTPN11.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 68 kDa in cell lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti PTPN11 antibody recognizes PTPN11 also known as tyrosine-protein phosphatase non-receptor type 11, PTP2C or SHPTP2. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPN11 contains two Src homology-2 domains which bind phospho-tyrosine domains. PTPs regulate numerous cellular functions including cell proliferation and oncogenic transformation.