Mouse monoclonal [2D7/3] antibody to Serotonin Transporter.
Specificity
This antibody recognises the serotonin transporter, also known as Sodium-dependent serotonin transporter, 5HT transporter or Solute carrier family 6 member 4. Serotonin transporter is a 630 amino acid ~70 kDa multiple pass endosomal membrane protein. Serotonin transporter is involved in the transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization and in regulating availability of serotonin to receptors of the serotonergic system.
Applications
IHC-Fr
Dilutions
IHC-Fr: 0.5 µg/ml - 1 µg/ml
Reactivity
Rat, Mouse
Immunogen
Rat serotonin transporter, N-terminus/GST fusion protein corresponding to amino acids 1-85.
Host
Mouse
Clonality
Monoclonal
Clone ID
2D7/3
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein G affinity chromatography of ascites.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Rat serotonin transporter antibody, clone 2D7/3 reacts with the serotonin transporter, also known as Sodium-dependent serotonin transporter, 5HT transporter or Solute carrier family 6 member 4. Serotonin transporter is a 630 amino acid ~70 kDa multiple pass endosomal membrane protein. Serotonin transporter is involved in the transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization and in regulating availability of serotonin to receptors of the serotonergic system.
Synonyms
5HT transporter, 5HTT, HTT, SLC6A4, Sodium-dependent serotonin transporter, Solute carrier family 6 member 4
