Anti-SDHB Antibody [SDHB/2382] - BSA and Azide free (A253128)

Mouse monoclonal [SDHB/2382] antibody to SDHB for WB.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-SDHB Antibody [SDHB/2382] - BSA and Azide free
Description
Mouse monoclonal [SDHB/2382] antibody to SDHB.
Specificity
Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST.
Applications
WB
Dilutions
WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 165-273, of human SDHB protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
SDHB/2382
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
32 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SDHB Antibody [SDHB/2382] (A249948).
Synonyms
Ip, Iron-sulfur subunit of complex II, Malate dehydrogenase [quinone] iron-sulfur subunit, SDH, SDH1, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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