Anti-S100 beta Antibody [S100B/4148] - BSA and Azide free (A316947)

Anti-S100 beta Antibody [S100B/4148] - BSA and Azide free

Mouse monoclonal [S100B/4148] antibody to S100 beta.

S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.

Flow Cytometry, IF, WB

Human brain or melanoma.

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, WB: 0.5-1 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-92) of human S100B protein. The exact sequence is proprietary.

Mouse

S100B/4148

IgG2c

kappa

Protein A/G chromatography.

1 mg/ml

10-12 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.