Specificity
This antibody recognises mouse serine-threonine kinase receptor-interacting protein 3 (RIP3). RIP3 is related to RIP and RIP2 but does not posses a death domain or CARD motif at its C-terminus. RIP3 activates NF-Kappa B and potently induces apoptosis.RIP3 is expressed in a range of tissues including the spleen, liver, testis, heart, brain and lung.