This antibody recognises PTEN, a tumour suppressor protein located on the human chromosome 10 that is often mutated in various types of advanced cancers.PTEN exhibits protein phosphatase activity and can suppress the growth of glioma cells.
Applications
IHC-Fr, WB, IP
Dilutions
IHC-Fr 1: 1:20 - 1:50, IP: 1:10 - 1:20, WB: 1:100
Reactivity
Human, Mouse
Immunogen
A peptide corresponding to 10 amino acids from a region towards to the C-terminus of native PTEN.
Host
Mouse
Clonality
Monoclonal
Clone ID
A2b1
Isotype
IgG1
Conjugate
Unconjugated
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti PTEN tumour suppressor antibody, clone A2b1, is specific for PTEN, a tumour suppressor protein located on the human chromosome 10 that is often mutated in various types of advanced cancers.PTEN exhibits protein phosphatase activity and can suppress the growth of glioma cells.
Synonyms
Inositol polyphosphate 3-phosphatase, MMAC1, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, TEP1