Recombinant Anti-PGP9.5 Antibody [UCHL1/8107R] (A315512)

Anti-PGP9.5 Antibody [UCHL1/8107R]

Recombinant rabbit monoclonal [UCHL1/8107R] antibody to PGP9.5.

This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.

Cerebellum.

IHC: 1-2 µg/ml

Human, Rat

Recombinant full-length human UCHL1 protein.

Rabbit

Monoclonal

UCHL1/8107R

kappa

Protein A/G chromatography.

200 µg/ml

20-30 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Neuron cytoplasmic protein 9.5, PGP 9.5, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1, UCH-L1, UCHL1