Recombinant Anti-PAX5 Antibody [rPAX5/4228] (A249564)

Anti-PAX5 Antibody [rPAX5/4228]

Recombinant mouse monoclonal [rPAX5/4228] antibody to PAX5.

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, within amino acids 235-382, of human PAX5 protein. The exact sequence is proprietary.

Mouse

Monoclonal

rPAX5/4228

IgG2a

kappa

Protein A/G chromatography.

200 µg/ml

42 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PAX5 Antibody [rPAX5/4228] - BSA and Azide free (A252744).

B-cell-specific transcription factor, BSAP, Paired box protein Pax-5