Recombinant Anti-pan Cytokeratin Antibody [Cocktail rPCK/6750] (A277944)

Anti-pan Cytokeratin Antibody [Cocktail rPCK/6750]

Recombinant mouse monoclonal [Cocktail rPCK/6750] antibody to pan Cytokeratin.

Anti-cytokeratin clone rPCK/6750 (CK rPCK/6750) demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, rPCK/6750 is reactive with most epithelial types, including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, intestinal epithelium of stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid, skin (positive on the basal layer and negative on the superficial layers of squamous epithelium), and apocrine and sweat glands. In tumors, rPCK/6750 is reactive with most carcinomas, including breast, transitional cell (TCC), renal cell (RCC), lung adenocarcinoma, lung small cell, lung squamous cell, endometrial, prostate, ovarian, hepatocellular (HCC), colorectal CA, stomach and thyroid. It is negative in certain normal tissues, including brain, lymphocytes and all cells of hematolymphoid origin, muscle, brain, nerves, endothelium and in certain tumors including most melanomas, sarcomas, lymphomas, primitive neuroectodermal tumors (PNET)/Ewings and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes, some endothelia, and some muscle cells.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Feline, Canine

Crude cytokeratin extract prepared from RT-4 and MCF-7 cells.

Mouse

Monoclonal

Cocktail rPCK/6750

IgG1

Protein A/G chromatography.

200 µg/ml

40-67 kDa (Multiple)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-pan Cytokeratin Antibody [Cocktail rPCK/6750] - BSA and Azide free (A278532).

CK-20, CK-2P, Cytokeratin-20, Cytokeratin-2P, K20, K2P, K76, Keratin, type I cytoskeletal 20, Keratin, type II cytoskeletal 2 oral, Keratin-20, Keratin-76, KRT20, KRT2B, KRT2P, KRT76, Protein IT, Type-II keratin Kb9