This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
Applications
Flow Cytometry, IP, ICC
Dilutions
Flow Cytometry: 2-4 µg/ml.
Reactivity
Human
Immunogen
Human platelets.
Host
Mouse
Clonality
Monoclonal
Clone ID
PAC-1
Isotype
IgM
Light Chains
kappa
Conjugate
Unconjugated
Purification
Purified by differential precipitation and solid-phase chromatography.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Tris Buffered Saline, pH 8, with 15 mM Sodium Azide.
Storage
Shipped at 4°C. Store at 2-8°C. Do not freeze!
Synonyms
C21-LRP, C21LRP, Chromosome 21 leucine-rich protein, Down syndrome critical region protein 2, DSCR2, PAC1, Proteasome assembly chaperone 1