Recombinant Anti-p75 NGF Receptor Antibody [NGFR/8590R] - BSA and Azide free (A316835)

Anti-p75 NGF Receptor Antibody [NGFR/8590R] - BSA and Azide free

Recombinant rabbit monoclonal [NGFR/8590R] antibody to p75 NGF Receptor.

It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

Neuronal axons, Schwann cells, and perineural cells of peripheral nerves, or tumors of nerve sheath differentiation e.g. Schwannoma, Neurofibroma. Soma and axons of sensory neurons, and ganglionic satellite cells. Melanomas.

IHC: 1-2 µg/ml

Human, Non-Human Primates

Recombinant human full-length p75 NGFR protein.

Rabbit

Monoclonal

NGFR/8590R

kappa

Protein A/G chromatography.

1 mg/ml

75 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.