Anti-p27 KIP 1 Antibody (A283417)

Anti-p27 KIP 1 Antibody

Rabbit polyclonal antibody to p27 KIP 1.

This antibody recognises cyclin-dependent kinase inhibitor p27 (p27), also known as cyclin-dependent kinase inhibitor 1B or p27Kip1. The protein is a cyclin-dependent kinase inhibitor (CKI) that belongs to the Cip/Kip protein family. As the name implies, CKIs play a role in the regulation of cyclin-dependent kinases (CDKs) and cyclin-CDK complexes. Aberrant p27Kip1. levels have been reported in breast and colorectal cancers (Sgambato et al. 1997, Ogino et al. 2007).

WB: 1:200

Human, Mouse, Rat

A peptide corresponding to the C-terminus of human p27/Kip1.

Rabbit

Polyclonal

IgG

Affinity chromatography.

Approximately 27 kDa when run under reducing conditions

Liquid

Supplied in Phosphate Buffered Saline with 0.2% Gelatin and 0.1% Sodium Azide.

Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti p27/Kip1 antibody recognizes cyclin-dependent kinase inhibitor p27 (p27), also known as cyclin-dependent kinase inhibitor 1B or p27Kip1. The protein is a cyclin-dependent kinase inhibitor (CKI) that belongs to the Cip/Kip protein family (Cerqueira et al. 2014). As the name implies, CKIs play a role in the regulation of cyclin-dependent kinases (CDKs) and cyclin-CDK complexes (Cerqueira et al. 2014).Aberrant p27Kip1. levels have been reported in breast and colorectal cancers (Sgambato et al. 1997, Ogino et al. 2007).

CDKN1B, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, KIP1, p27Kip1