Anti-Osteocalcin Antibody [6F9G4E10] (A279493)

Anti-Osteocalcin Antibody [6F9G4E10]

Mouse monoclonal [6F9G4E10] antibody to Osteocalcin.

This antibody recognises intact human osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin.Osteocalcin (Bone Gla Protein) is a 49 amino acid ~5.8 kDa single chain vitamin K dependent protein, made by osteoblasts and major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

Human

This antibody does not cross react with Bovine, Mouse, or Rat

Recombinant human osteocalcin GST fusion protein.

Mouse

Monoclonal

6F9G4E10

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Osteocalcin antibody, clone 6F9G4E10 recognizes intact human osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact bovine osteocalcin.Osteocalcin (Bone Gla Protein) is a 49 amino acid ~5.8 kDa single chain vitamin K dependent protein, made by osteoblasts and major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

BGLAP, BGP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein