Recombinant rabbit monoclonal [OCT4/7347R] antibody to OCT4.
Specificity
OCT4 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.
Applications
IHC-P
Positive Control
Raji or U-937 cells. Human seminoma or testicular carcinoma
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment of human OCT-4/POU5F1 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
OCT4/7347R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
38.6 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Oct-3, OCT3, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, OTF-3, OTF3, POU domain, class 5, transcription factor 1, POU5F1