Recombinant Anti-OCT4 Antibody [OCT4/6847R] (A315423)

Anti-OCT4 Antibody [OCT4/6847R]

Recombinant rabbit monoclonal [OCT4/6847R] antibody to OCT4.

OCT4 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells.OCT4 is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.

Raji or U-937 cells. Human seminoma or testicular carcinoma

IHC: 1-2 µg/ml

Human

Recombinant fragment of human OCT-4/POU5F1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

OCT4/6847R

IgG

Protein A/G chromatography.

200 µg/ml

38.6 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Oct-3, OCT3, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, OTF-3, OTF3, POU domain, class 5, transcription factor 1, POU5F1