Anti-Notch1 Antibody [mN1A] (FITC) (A281237)

$420

Mouse monoclonal [mN1A] antibody to Notch1 (FITC) for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-Notch1 Antibody [mN1A] (FITC)
Description
Mouse monoclonal [mN1A] antibody to Notch1 (FITC).
Specificity
This antibody recognises Notch 1, one of the four major transmembrane receptors (Notch 1-4) of the Notch signaling pathway, which is activated through binding to DSL domain-containing membrane-bound specific ligands.Notch 1 is expressed in a range of cells including haematopoietic cells in mouse foetal liver, adult thymus and bone marrow. Notch 1 signaling plays a role in follicular differentiation, tissue homeostasis, and in both CD4+ and CD8+ cell maturation in the thymus.
Applications
Flow Cytometry
Dilutions
FC 1: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl
Reactivity
Mouse, Human
Immunogen
Synthetic peptide corresponding to the cdc10-NCR region within mouse Notch1.
Host
Mouse
Clonality
Monoclonal
Clone ID
mN1A
Isotype
IgG1
Conjugate

FITC

Excitation: 490nm, Emission: 525nm

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
General Notes
Mouse anti Mouse Notch 1 antibody, clone mN1A recognizes Notch 1, one of the four major transmembrane receptors (Notch 1-4) of the Notch signaling pathway, which is activated through binding to DSL domain-containing membrane-bound specific ligands.Notch 1 is expressed in a range of cells including haematopoietic cells in mouse foetal liver, adult thymus and bone marrow. Notch 1 signaling plays a role in follicular differentiation, tissue homeostasis, and in both CD4+ and CD8+ cell maturation in the thymus.
Synonyms
hN1, Neurogenic locus notch homolog protein 1, Notch 1, TAN1, Translocation-associated notch protein TAN-1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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