Nemolizumab Biosimilar - Anti-IL-31RA Antibody (A332189)

Nemolizumab Biosimilar - Anti-IL-31RA Antibody

Recombinant humanized monoclonal antibody to IL-31RA.

ELISA, Flow Cytometry

ELISA 1:5,000-1:10,000, Flow Cytometry: 1:100

Human

Humanized

Monoclonal

IgG2 (C14S, R16K, E20G, S21G, C102S, H147Q, R234Q, S257A, Q298E)

Affinity chromatography.

Reconstitution dependent.

Reconstitute with distilled sterile water.

Lyophilized from sterile Phosphate Buffered Saline, pH 7.4. Normally 5%–8% Trehalose is added as a protectant before lyophilization.

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Prior to reconstitution, centrifuge the vial at 5,000g for 3-5 minutes at room temperature. Reconstitute with appropriate volume of distilled sterile water to bring product to 1mg/ml concentration. After addition of distilled sterile water, mix by gentle tapping. Note: It is not recommended to vortex or vigorously pipette the sample.

CRL3, Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, Gp130-like receptor, GPL, hGLM-R, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL31RA, Interleukin-31 receptor subunit alpha, ZcytoR17