Anti-NCAM1 Antibody [123C3] (A278980)

Anti-NCAM1 Antibody [123C3]

Mouse monoclonal [123C3] antibody to NCAM1.

This antibody recognises human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180 kDa form, while hemopoietic cells express the 140 kDa isoform. recognises both the 140 kDa and the 180 kDa isoform of the CD56 protein.In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.

IHC-P, IHC-Fr, ELISA, Flow Cytometry

Flow Cytometry: 1:25 - 1:10 Pack Size: 0.1 mg 1:50 Pack Size: 0.2 mg, IHC-P: 1:100 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

This antibody does not cross react with Rat

Membrane preparation of small lung carcinoma.

Mouse

Monoclonal

123C3

IgG1

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD56 antibody, clone 123C3 recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 molecule is a cell surface glycoprotein expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180 kDa form, while hemopoietic cells express the 140 kDa isoform. Mouse anti Human CD56 antibody, clone 123C3 recognizes both the 140 kDa and the 180 kDa isoform of the CD56 protein.In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.

CD56, N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1