Anti-NCAM1 Antibody [123A8] - BSA and Azide free (A252656)

Anti-NCAM1 Antibody [123A8] - BSA and Azide free

Mouse monoclonal [123A8] antibody to NCAM1.

This antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

IF, IHC-P

IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Membrane preparation of a small cell lung carcinoma.

Mouse

Monoclonal

123A8

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

180 kDa / 145 kDa / 125 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD56, N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1