Recombinant rabbit monoclonal [NAPSA/7043R] antibody to NAPSIN A.
Specificity
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
Applications
IHC-P
Positive Control
Human lung or lung adenocarcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human Napsin-A protein fragment (aa1-100). The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
NAPSA/7043R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A chromatography.
Concentration
200 µg/ml
Molecular Weight
37 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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