Recombinant Anti-MYH11 Antibody [MYH11/7087R] (A278035)

Anti-MYH11 Antibody [MYH11/7087R]

Recombinant rabbit monoclonal [MYH11/7087R] antibody to MYH11.

Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 1-100, of human Myosin (smooth muscle).

Rabbit

Monoclonal

MYH11/7087R

IgG

Protein A/G chromatography.

200 µg/ml

227 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MYH11 Antibody [MYH11/7087R] - BSA and Azide free (A278623).

KIAA0866, Myosin heavy chain 11, Myosin heavy chain, smooth muscle isoform, Myosin-11, SMMHC