Anti-Mucin 5AC Antibody [SPM297] - BSA and Azide free (A252612)

Anti-Mucin 5AC Antibody [SPM297] - BSA and Azide free

Mouse monoclonal [SPM297] antibody to Mucin 5AC.

This antibody recognizes the peptide core of gastric mucin M1 (1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Monkey, Rabbit, Feline, Mouse, Rat, Porcine, Hedgehog, Chicken

This antibody does not cross react with Bovine.

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient.

Mouse

Monoclonal

SPM297

IgG1

Protein A/G chromatography.

1 mg/ml

>1,000 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Mucin 5AC Antibody [SPM297] (A249432).