Anti-Mucin 5AC Antibody [45M1] (A249431)

Anti-Mucin 5AC Antibody [45M1]

Mouse monoclonal [45M1] antibody to Mucin 5AC.

This antibody recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

IHC-P: 1-2 µg/ml

Human, Monkey, Rabbit, Feline, Mouse, Rat, Porcine, Hedgehog, Chicken

This antibody does not cross react with Bovine.

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient.

Mouse

Monoclonal

45M1

kappa

Protein A/G chromatography.

200 µg/ml

>1,000 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Mucin 5AC Antibody [45M1] - BSA and Azide free (A252611).