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Anti-M-CSF Antibody - BSA and Azide free (A283265)

$670

Rabbit polyclonal antibody to M-CSF for WB, ELISA, IHC-P and Functional Assays.

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-7 business days.
Name
Anti-M-CSF Antibody - BSA and Azide free
Description
Rabbit polyclonal antibody to M-CSF.
Specificity
This antibody recognises human M-CSF (Macrophage Colony-Stimulating Factor), a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells.Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor), and facilitates haematopoietic recovery following bone marrow transplantation.
Applications
WB, ELISA, IHC-P, Functional Assays
Dilutions
ELISA: 0.5 - 2 µg/ml, Functional Assays: 0.02 - 0.03 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant human M-CSF.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human M-CSF antibody recognizes human M-CSF (Macrophage Colony-Stimulating Factor), a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells.Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor), and facilitates haematopoietic recovery following bone marrow transplantation.
Synonyms
CSF-1, CSF1, Lanimostim, Macrophage colony-stimulating factor 1, MCSF, PG-M-CSF, Proteoglycan macrophage colony-stimulating factor
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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