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Anti-Liver X Receptor beta Antibody [LXRB/2731] (A250282)

Mouse monoclonal [LXRB/2731] antibody to Liver X Receptor beta for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-Liver X Receptor beta Antibody [LXRB/2731]
Description
Mouse monoclonal [LXRB/2731] antibody to Liver X Receptor beta.
Specificity
The liver X receptors, LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.
Applications
ELISA
Reactivity
Human
Immunogen
Recombinant full-length human NR1H2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
LXRB/2731
Isotype
IgG2c
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
56 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Liver X Receptor beta Antibody [LXRB/2731] - BSA and Azide free (A253462).
Synonyms
LXRB, NER, NR1H2, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear receptor, UNR
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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