Recombinant Anti-LI Cadherin Antibody [rCDH17/8514] - BSA and Azide free (A316632)

Anti-LI Cadherin Antibody [rCDH17/8514] - BSA and Azide free

Recombinant mouse monoclonal [rCDH17/8514] antibody to LI Cadherin.

It recognizes a protein of 120kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 242-418) of human Cadherin 17 protein (CDH17). The exact sequence is proprietary.

Mouse

Monoclonal

rCDH17/8514

kappa

Protein A chromatography.

1 mg/ml

120 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CDH17, Intestinal peptide-associated transporter HPT-1, LI-cadherin, Liver-intestine cadherin