Anti-Lactate Dehydrogenase Antibody (A282828)

Anti-Lactate Dehydrogenase Antibody

Sheep polyclonal antibody to Lactate Dehydrogenase.

This antibody recognises LDH2-5, and exhibits low reactivity with LDH1. L-lactate dehydrogenase isozymes exist as tetramers of two subunits with LDH-1 composed for 4 β chains and LDH-5 composed of 4 α chains. LDH-2 =3β:1α, LDH-3 = 2β:2α, LDH-4 = 1β:3α. Mutations in the LDHA gene can lead to the development of glycogen storage disease 11 (GSD11), a condition typified by myogloinurea, fatigue and pain.

WB, ELISA

WB: 1:100 - 1:500

Human

Native highly purified lactate dehydrogenase 5.

Sheep

Polyclonal

IgG

5 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Sheep anti lactate dehydrogenase 5 antibody reacts with LDH2-5, and exhibits low reactivity with LDH1. L-lactate dehydrogenase isozymes exist as tetramers of two subunits with LDH-1 composed for 4 ß chains and LDH-5 composed of 4 a chains. LDH-2 =3ß:1a, LDH-3 = 2ß:2a, LDH-4 = 1ß:3a (Boyer et al. 1963).Mutations in the LDHA gene can lead to the development of glycogen storage disease 11 (GSD11), a condition typified by myogloinurea, fatigue and pain.

Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, Renal carcinoma antigen NY-REN-59