Anti-Ki67 Antibody [MKI67/6582] (A315214)

Anti-Ki67 Antibody [MKI67/6582]

Mouse monoclonal [MKI67/6582] antibody to Ki67.

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

Flow Cytometry, IF, WB, IHC-P

Any actively proliferating cells. Human skin, tonsil or lymph node.

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant human Ki67 protein fragment (around Amino Acids 2293-2478). The exact sequence is proprietary.

Mouse

Monoclonal

MKI67/6582

kappa

Protein A/G chromatography.

200 µg/ml

345 kDa / 395 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Antigen identified by monoclonal antibody Ki-67, Antigen KI-67, Antigen Ki67, MKI67, Proliferation marker protein Ki-67