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Anti-IRF9 Antibody [PCRP-IRF9-2F8] (A277529)

Mouse monoclonal [PCRP-IRF9-2F8] antibody to IRF9 for Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-IRF9 Antibody [PCRP-IRF9-2F8]
Description
Mouse monoclonal [PCRP-IRF9-2F8] antibody to IRF9.
Specificity
Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Applications
Flow Cytometry, IF
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human IRF9 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-IRF9-2F8
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
43.34 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-IRF9 Antibody [PCRP-IRF9-2F8] - BSA and Azide free (A278117).
Synonyms
IFN-alpha-responsive transcription factor subunit, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, Transcriptional regulator ISGF3 subunit gamma
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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