Anti-IRF7 Antibody (A283049)

Anti-IRF7 Antibody

Rabbit polyclonal antibody to IRF7.

This antibody recognises human interferon regulatory factor 7 (IRF7), a ~54 kDa transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.

WB: 0.5 - 1 µg/ml

Human

A peptide corresponding to 14 amino acids near the centre of human IRF7.

Rabbit

Polyclonal

IgG

Approximately 51 kDa in 293 whole cell lysate.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human IRF7 antibody detects human interferon regulatory factor 7 (IRF7), a ~54 kDa transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.

Interferon regulatory factor 7, IRF-7