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Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)

SDS-PAGE - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.com SEC-HPLC - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.com FACS - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.com Research in vivo - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.com
Recombinant Antibody
$305
Product Datasheet

Recombinant human monoclonal antibody to CTLA4 for ELISA, FACS, Functional Assay and In Vivo.

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Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 12-18 business days.

  • Specifications

Name
Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free
Description
Recombinant human monoclonal antibody to CTLA4.
Applications
ELISA, FACS, Functional Assay, In Vivo
Reactivity
Human, Mouse, Cynomolgus Macaque
Host
Human
Clonality
Monoclonal
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A affinity chromatography.
Concentration
Reconstitution dependent.
Molecular Weight
This antibody has a predicted MW of 145.38 kDa.
Purity
> 95% (by SDS-PAGE and SEC-HPLC).
Product Form
Lyophilized
Reconstitution
Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!
Formulation
Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
Synonyms
CD152, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Suitable Secondaries
See all Anti-Human IgG Secondaries →
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

  • Scientific Validation DataValidation Data (4)

SDS-PAGE - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.comEnlarge Image

SDS-PAGE - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)

SDS-PAGE analysis of Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.
SEC-HPLC - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.comEnlarge Image

Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)

SEC-HPLC analysis of Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) confirms that the purity of this antibody is 99.37%.
FACS - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.comEnlarge Image

Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)

Human CTLA-4 & Human PD-1 CHO-K cells were stained with Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50 = 0.2270 µg/ml.
Research in vivo - Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) - Antibodies.comEnlarge Image

Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)

Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516) inhibited the tumor growth of MC38 on huCTLA-4 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 99.3% at 0.88 mpk at D37.
Publishing research using Ipilimumab Biosimilar - Anti-CTLA4 Antibody - Low endotoxin, Azide free (A323516)? Please let us know so that we can list the citation on this page.

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