Anti-Interferon gamma Antibody [CC302] (A280030)

Anti-Interferon gamma Antibody [CC302]

Mouse monoclonal [CC302] antibody to Interferon gamma.

This antibody recognises bovine interferon-gamma, a 143 amino acid cytokine with potent activating, antiviral and anti proliferative properties, produced as a pro-peptide with an additional 23 amino acid N-terminal signal peptide sequence having a molecular weight of ~20 kDa. IFN? is predominantly secreted by activated T lymphocytes in response to specific mitogens as a result of infection. Mouse anti bovine ? interferon antibody, clone CC302 has been demonstrated to be reactive to a number of mammalian species including human, sheep, dog, pig, goat and mink. Mouse anti Bovine IFN? antibody, clone CC302 has been used successfully for the evaluation of ? interferon levels in the sera of calves naturally infected with M. avium. subsp paratuberculosis as a detection reagent using an ELISA.

Flow Cytometry, ELISA

FC 1: 1:100 - 1:500

Bovine, Human, Pig, Dog, Horse, Sheep, Mustelid, Goat, Dolphin, Ferret, Mink, Fin Whale, Rabbit

Mouse

Monoclonal

CC302

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Bovine IFN? antibody, clone CC302 recognizes bovine interferon-gamma, a 143 amino acid cytokine with potent activating, antiviral and anti proliferative properties, produced as a pro-peptide with an additional 23 amino acid N-terminal signal peptide sequence having a molecular weight of ~20 kDa. IFN? is predominantly secreted by activated T lymphocytes in response to specific mitogens as a result of infection (Rhodes et al. 2000).Mouse anti bovine ? interferon antibody, clone CC302 has been demonstrated to be reactive to a number of mammalian species including human, sheep, dog, pig, goat and mink (Pedersen et al. 2002). Mouse anti Bovine IFN? antibody, clone CC302 has been used successfully for the evaluation of ? interferon levels in the sera of calves naturally infected with M. avium. subsp paratuberculosis (Appana et al. 2013) as a detection reagent using an ELISA.