Anti-Integrin beta 3 Antibody [Y2/51] (FITC) (A282015)

Anti-Integrin beta 3 Antibody [Y2/51] (FITC)

Mouse monoclonal [Y2/51] antibody to Integrin beta 3 (FITC).

This antibody recognises CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

PHA stimulated peripheral blood cells.

Mouse

Monoclonal

Y2/51

IgG1

Protein A affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human CD61 antibody, clone Y2/51 recognizes CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.

CD61, GP3A, GPIIIa, Integrin beta-3, ITGB3, Platelet membrane glycoprotein IIIa

This product is for research use only. It is not intended for diagnostic or therapeutic use.