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Anti-Integrin beta 3 Antibody [F11] (FITC) (A280413)

This product is discontinued

Anti-Integrin beta 3 Antibody [F11] (FITC) (A280413) has been discontinued and is no longer available.

View all Integrin beta 3 Antibodies.

Name
Anti-Integrin beta 3 Antibody [F11] (FITC)
Description
Mouse monoclonal [F11] antibody to Integrin beta 3 (FITC).
Specificity
This antibody recognises the rat CD61 cell surface antigen, also known as the integrin b3 chain.CD61 is expressed by platelets, megakaryocytes and osteoclasts.Clone F11 has been shown to inhibit the in vitro attachment of osteoclasts to various proteins including vitronectin, fibrinogen and von Willebrand Factor.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Rat
Immunogen
Bone cell suspension from SD rats.
Host
Mouse
Clonality
Monoclonal
Clone ID
F11
Isotype
IgG1
Conjugate

FITC

Excitation: 490nm, Emission: 525nm

Concentration
100 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
General Notes
Mouse anti Rat CD61 antibody, clone F11 recognizes the rat CD61 cell surface antigen, also known as the integrin b3 chain.CD61 is expressed by platelets, megakaryocytes and osteoclasts.Clone F11 has been shown to inhibit the in vitro attachment of osteoclasts to various proteins including vitronectin, fibrinogen and von Willebrand Factor (Sick et al. 2009).
Synonyms
CD61, GP3A, GPIIIa, Integrin beta-3, ITGB3, Platelet membrane glycoprotein IIIa
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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