Recombinant rabbit monoclonal [ITGB1/8744R] antibody to Integrin beta 1.
Specificity
Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
Applications
ELISA, IHC-P
Positive Control
Human kidney.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human ITGB1 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ITGB1/8744R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
110 kDa (non-reduced) / 130 kDa (reduced)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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