Anti-Integrin beta 1 Antibody [HM beta 1-1] - BSA and Azide free (A280608)

Overview
Specifications

Hamster monoclonal [HM beta 1-1] antibody to Integrin beta 1 for Flow Cytometry, IP and Functional Assays.

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Alternative Formats and ConjugatesAlternative Formats

FITC PE Unconjugated

Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 5-7 business days.

Specifications

Name

Anti-Integrin beta 1 Antibody [HM beta 1-1] - BSA and Azide free

Description

Hamster monoclonal [HM beta 1-1] antibody to Integrin beta 1.

Specificity

This antibody recognises the murine integrin beta 1 subunit (CD29), a ~110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Hamster anti Mouse CD29 antibody, clone HM beta 1-1 is reported to inhibit beta 1 integrin mediated adhesion.

Applications

Flow Cytometry, IP, Functional Assays

Dilutions

Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Reactivity

Mouse, Rat

Immunogen

Purified mouse VLA-4 antigen.

Host

Hamster

Clonality

Monoclonal

Clone ID

HM beta 1-1

Isotype

IgG

Conjugate

Unconjugated

Purification

Protein G affinity chromatography of tissue culture supernatant.

Concentration

1 mg/ml

Product Form

Liquid

Formulation

Supplied in Phosphate Buffered Saline.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles.

General Notes

Hamster anti Mouse CD29 antibody, clone HM beta 1-1 recognizes the murine integrin beta 1 subunit (CD29), a ~110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Hamster anti Mouse CD29 antibody, clone HM beta 1-1 is reported to inhibit beta 1 integrin mediated adhesion (Noto et al. 1995).

Synonyms

CD29, Fibronectin receptor subunit beta, FNRB, Glycoprotein IIa, GPIIA, Integrin beta-1, ITGB1, MDF2, MSK12, VLA-4 subunit beta

Suitable Secondaries

See all Anti-Hamster IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

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