Anti-Integrin alpha 2 Antibody [AK7] - BSA and Azide free
Description
Mouse monoclonal [AK7] antibody to Integrin alpha 2.
Specificity
This antibody recognises the integrin alpha 2 subunit, a ~160 kDa glycoprotein that non-covalently associates with the ~130 kDa integrin beta 1 subunit to form the VLA-2 complex.CD49b is expressed by platelets, long term cultivated T cells, approximately 50% of monocytes and most adherent cell lines. Mouse anti Human CD49b antibody, clone AK7 inhibits cell attachment to collagen.
Applications
Flow Cytometry, IHC-Fr, Functional Assays
Dilutions
Flow Cytometry: 1:50 - 1:100, IHC-Fr 2: 1:500 - 1:1,000, Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Reactivity
Human, Cynomolgus monkey, Rhesus Monkey, Baboon
Host
Mouse
Clonality
Monoclonal
Clone ID
AK7
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Mouse anti Human CD49b antibody, clone AK7 recognizes the integrin alpha 2 subunit, a ~160 kDa glycoprotein that non-covalently associates with the ~130 kDa integrin beta 1 subunit to form the VLA-2 complex.CD49b is expressed by platelets, long term cultivated T cells, approximately 50% of monocytes and most adherent cell lines. Mouse anti Human CD49b antibody, clone AK7 inhibits cell attachment to collagen.
Synonyms
CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, ITGA2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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