Anti-Integrin alpha 2 Antibody [16B4] (PE) (A279043)

Anti-Integrin alpha 2 Antibody [16B4] (PE)

Mouse monoclonal [16B4] antibody to Integrin alpha 2 (PE).

This antibody recognises human CD49b, also known as integrin a2, collagen receptor, Platelet membrane glycoprotein Ia or VLA-2 subunit alpha. CD49b is a 1181 amino acid ~160 kDa single pass type-1 transmembrane glycoprotein possessing multiple FG-GAP repeats and a single VWFA domain. Mouse anti human CD49b antibody, clone 16B4 is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labeled human cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots.

Flow Cytometry: Neat

Human

This antibody does not cross react with Rat

Purified human beta 1 preparation from HT1080 fibrosarcoma cell extract.

Mouse

Monoclonal

16B4

IgG1

Protein G affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light.

Mouse anti Human CD49b antibody, clone 16B4 recognizes human CD49b, also known as integrin a2, collagen receptor, Platelet membrane glycoprotein Ia or VLA-2 subunit alpha. CD49b is a 1181 amino acid ~160 kDa single pass type-1 transmembrane glycoprotein possessing multiple FG-GAP repeats and a single VWFA domain. Mouse anti human CD49b antibody, clone 16B4 is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labeled human cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots.

CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, ITGA2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha

This product is for research use only. It is not intended for diagnostic or therapeutic use.