Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free (A252220)

Name: Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free
Brand: Antibodies.com
SKU: A252220
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [E2-E3 + 2D11-H5] antibody to Insulin for IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 4-6 business days.

Specifications

Name

Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free

Description

Mouse monoclonal [E2-E3 + 2D11-H5] antibody to Insulin.

Specificity

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Applications

IHC-P

Dilutions

IHC-P: 1-2 µg/ml

Reactivity

Human, Bovine, Porcine, Rabbit, Mouse

Immunogen

Purified pig insulin, conjugated to KLH.

Host

Mouse

Clonality

Oligoclonal

Clone ID

E2-E3 + 2D11-H5

Isotype

IgG1, kappa + IgG1, kappa

Conjugate

Unconjugated

Concentration

1 mg/ml

Molecular Weight

6 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen. This antibody is also known as Clone INS04 + INS05.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Insulin Antibody [E2-E3 + 2D11-H5] (A249040).

Synonyms

INS

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation DataValidation Data (2)

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Immunohistochemistry - Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free (A252220)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreas using Anti-Insulin Antibody [E2-E3+2D11-H5].

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SDS-PAGE - Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free (A252220)

SDS-PAGE analysis of Anti-Insulin Antibody [E2-E3+2D11-H5] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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