Anti-IL-6 Antibody [J06-1E12] (Biotin) (A280762)

Anti-IL-6 Antibody [J06-1E12] (Biotin)

Mouse monoclonal [J06-1E12] antibody to IL-6 (Biotin).

This antibody recognises human interleukin 6, also known as B-cell stimulatory factor 2, CTL differentiation factor, Hybridoma growth factor or Interferon beta-2. Interleukin-6 is a 183 amino acid ~24 kDa cytokine with a wide range of biological activities. Interleukin-6 is a potent inducer of the acute phase response, acts as a lymphoid cell growth factor acting on B cells, T cells and hybridoma cells.Variations in the interleukin-6 gene modulates susceptibility to onset of juvenile systemic rheumatoid arthritis (RASJ) an inflammatory disorder with early onset and featuring lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis. The biotinylated Mouse anti Human interleukin-6 antibody, clone J06-1E12 (MCA6334B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human interleukin-6 antibody, clone C01-1E8 (MCA6333GA) as the capture antibody.

ELISA: 1 µg/ml

Human

E. coli derived recombinant human full length interleukin-6 (Val30-Met212) .

Mouse

Monoclonal

J06-1E12

IgG1

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human interleukin-6 antibody, clone J06-1E12 recognizes human interleukin 6, also known as B-cell stimulatory factor 2, CTL differentiation factor, Hybridoma growth factor or Interferon beta-2. Interleukin-6 is a 183 amino acid ~24 kDa cytokine with a wide range of biological activities. Interleukin-6 is a potent inducer of the acute phase response, acts as a lymphoid cell growth factor acting on B cells, T cells and hybridoma cells.Variations in the interleukin-6 gene modulates susceptibility to onset of juvenile systemic rheumatoid arthritis (RASJ) an inflammatory disorder with early onset and featuring lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis (Fishman et al. 1998).The biotinylated Mouse anti Human interleukin-6 antibody, clone J06-1E12 (MCA6334B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human interleukin-6 antibody, clone C01-1E8 (MCA6333GA) as the capture antibody.

B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL6, Interferon beta-2, Interleukin-6

This product is for research use only. It is not intended for diagnostic or therapeutic use.