Anti-IL-21 Antibody (Biotin) - BSA and Azide free (A282237)

Anti-IL-21 Antibody (Biotin) - BSA and Azide free

Rabbit polyclonal antibody to IL-21 (Biotin).

This antibody recognises mouse interleukin-21 (IL-21), a pleiotropic cytokine and member of the IL-15/IL-21 family, secreted by stimulated CD4+ T cells, which enhances stimulated B-cell proliferation/differentiation, the proliferation of bone marrow progenitor cells, and increases the activity of NK cells and disease-specific CD8+ T-cells.IL-21 signals through binding to the specific type I cytokine receptor IL-21R, coupled with the common cytokine receptor g chain (gc), initiating the activation of the JAK/STAT signalling pathway.

WB, ELISA

ELISA: 0.25 - 1 µg/ml, WB: 0.1 - 0.2 µg/ml

Mouse

Recombinant mouse IL-21.

Rabbit

Polyclonal

IgG

100 µg/ml after reconstitution.

Lyophilized

Reconstitute with 0.5 ml of sterile Phosphate Buffered Saline containing 0.1% Bovine Serum Albumin. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Mouse Interleukin-21 antibody recognizes mouse interleukin-21 (IL-21), a pleiotropic cytokine and member of the IL-15/IL-21 family, secreted by stimulated CD4+ T cells, which enhances stimulated B-cell proliferation/differentiation, the proliferation of bone marrow progenitor cells, and increases the activity of NK cells and disease-specific CD8+ T-cells.IL-21 signals through binding to the specific type I cytokine receptor IL-21R, coupled with the common cytokine receptor g chain (gc), initiating the activation of the JAK/STAT signalling pathway.

IL21, Interleukin-21, Za11

This product is for research use only. It is not intended for diagnostic or therapeutic use.