General Notes
Mouse anti Human insulin-like growth factor 1 antibody, clone M23 recognizes human IGF-1, also known as Mechano growth factor, Somatomedin-C or Insulin-like growth factor I. IGF-1 is a 195 amino acid ~ kDa secreted peptide bearing an N-terminal signal peptide and a propeptide together accounting for the N-terminal 48 amino acid residues. There is a second C-terminal propeptide region, known as the 'E-peptide', also cleaved during processing to yeild the 70 amino acid acivie secreted IGF-1 peptide. IGF-1 is functionally related to insulin but with a higher growth-promoting activity.Mouse anti Human insulin-like growth factor 1 antibody, clone M23 has not been cross-adsorbed and may react with similar peptides from related species.