Anti-IGF1 Antibody [M23] (A248929)

Anti-IGF1 Antibody [M23]

Mouse monoclonal [M23] antibody to IGF1.

This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Mouse, Rat, Rabbit

Purified human IGF-1 protein.

Mouse

Monoclonal

M23

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

~7.6 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-IGF1 Antibody [M23] - BSA and Azide free (A252109).

IBP1, IGF-I, Insulin-like growth factor I, Mechano growth factor, MGF, Somatomedin-C