Anti-ICAM1 Antibody [ICAM1/6606] - BSA and Azide free (A316506)

Anti-ICAM1 Antibody [ICAM1/6606] - BSA and Azide free

Mouse monoclonal [ICAM1/6606] antibody to ICAM1.

Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

Raji, HeLa or SW480 cells. Human tonsil.

IHC: 1-2 µg/ml

Human

Recombinant fragment of human ICAM1. The exact sequence is proprietary.

Mouse

Monoclonal

ICAM1/6606

kappa

Protein A/G chromatography.

1 mg/ml

85-115 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ICAM-1, Intercellular adhesion molecule 1, Major group rhinovirus receptor