Anti-ICAM1 Antibody [1A29] (A279069)

Anti-ICAM1 Antibody [1A29]

Mouse monoclonal [1A29] antibody to ICAM1.

This antibody recognises the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a ~90 kDa adhesion molecule belonging to the immunoglobulin superfamily.CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and plays an important role in various cell-cell interactions in the immune system. Cross-linking of ICAM-1 using clone 1A29 induces calcium signaling. Mouse anti Rat CD54 antibody, clone 1A29 inhibits homotypic aggregation of cells including PHA blasts.

WB, IHC-P, IP, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:25 - 1:50, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Rat

Rat Ax cells (a HEV derived cell line).

Mouse

Monoclonal

1A29

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Rat CD54 antibody, clone 1A29 recognizes the rat CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1), a ~90 kDa adhesion molecule belonging to the immunoglobulin superfamily.CD54 is a cell surface ligand of the lymphocyte integrin, LFA-1 and plays an important role in various cell-cell interactions in the immune system. Cross-linking of ICAM-1 using clone 1A29 induces calcium signaling (Etienne et al. 1998).Mouse anti Rat CD54 antibody, clone 1A29 inhibits homotypic aggregation of cells including PHA blasts (Tamatani & Miyasaka 1990).

ICAM-1, Intercellular adhesion molecule 1, Major group rhinovirus receptor