Recombinant Anti-HSP60 Antibody [rHSPD1/6497] (A277894)

Anti-HSP60 Antibody [rHSPD1/6497]

Recombinant mouse monoclonal [rHSPD1/6497] antibody to HSP60.

This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone rHSPD1/6497, unlike LK2, This antibody recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.

WB, IHC-P

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Mouse, Rat, Hamster, Sheep, Rabbit, Bovine, Canine, Porcine, Monkey, Chicken

Recombinant full-length human HSP60 protein.

Mouse

Monoclonal

rHSPD1/6497

IgG1

Protein A/G chromatography.

200 µg/ml

60 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HSP60 Antibody [rHSPD1/6497] - BSA and Azide free (A278482).