Anti-Horse IgE Antibody [3H10] (HRP) (A279309)

Anti-Horse IgE Antibody [3H10] (HRP)

Mouse monoclonal [3H10] antibody to Horse IgE (HRP).

This antibody recognises native equine IgE and does not cross react with equine IgM, IgA or IgG.IgE is an immunoglobulin primarily produced from plasma cells and, in normal serum, present at very low concentrations. IgE is important in both type 1 hypersensitivity and immunity to parasite infections, in particular parasitic worms where equine IgE levels are significantly elevated following infection.Monoclonal antibodies to equine IgE are of particular relevance to research into insect bite sensitivity, one of the most widely studied allergic diseases in equid species (Schaffartzik, A. et al. 2012).

ELISA: 1:500 - 1:5,000

Horse

Equine IgE.

Mouse

Monoclonal

IgG1

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.01% Thiomersal.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Horse IgE, clone 3H10, recognizes native equine IgE and does not cross react with equine IgM, IgA or IgG.IgE is an immunoglobulin primarily produced from plasma cells and, in normal serum, present at very low concentrations. IgE is important in both type 1 hypersensitivity and immunity to parasite infections, in particular parasitic worms where equine IgE levels are significantly elevated following infection.Monoclonal antibodies to equine IgE are of particular relevance to research into insect bite sensitivity, one of the most widely studied allergic diseases in equid species (Schaffartzik, A. et al. 2012).

This product is for research use only. It is not intended for diagnostic or therapeutic use.