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Anti-HER2 Antibody [HRB2/258] (A248453)

Mouse monoclonal [HRB2/258] antibody to HER2 for ELISA, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-HER2 Antibody [HRB2/258]
Description
Mouse monoclonal [HRB2/258] antibody to HER2.
Specificity
This antibody recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. C-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Applications
ELISA, Flow Cytometry, IF
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human, Rat
Immunogen
Recombinant extracellular domain of human HER-2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
HRB2/258
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
185 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HER2 Antibody [HRB2/258] - BSA and Azide free (A251635).
Synonyms
CD340, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEU, NGL, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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