Anti-HDAC5 (phospho Ser498) Antibody (A283631)

Anti-HDAC5 (phospho Ser498) Antibody

Rabbit polyclonal antibody to HDAC5 (phospho Ser498).

This antibody recognises Histone deacetylase 5, also known as HDAC5, when phosphorylated at serine 498. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Histone deacetylase 5 is a class II histone deacetylase, which shuttles back and forth between nucleus and cytoplasm.Histone deacetylase 5 is phosphorylated at serine 498 by Protein kinase D (PKD) and Calcium/ calmodulin-dependent protein kinase (CaMK) (McKinsey et al. 2000, Ha et al. 2008).

WB, IHC-P

IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Ser498 of human histone deacetylase 5.

Rabbit

Polyclonal

IgG

Lot Specific

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Histone deacetylase 5 (pSer498) antibody recognizes histone deacetylase 5, also known as HDAC5, when phosphorylated at serine 498. Histone deacetylases are chromatin-modifying enzymes that are involved in regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Histone deacetylase 5 is a class II histone deacetylase, which shuttles back and forth between nucleus and cytoplasm.Histone deacetylase 5 is phosphorylated at serine 498 by Protein kinase D (PKD) and Calcium/ calmodulin-dependent protein kinase (CaMK) (McKinsey et al. 2000, Ha et al. 2008).

Antigen NY-CO-9, HD5, Histone deacetylase 5, KIAA0600